← all papers · autophagy (4) Science journalism, not medical advice.
- Five Cell Death Routes Killing Sperm2026-06-16
Narrative review maps five regulated cell death pathways — apoptosis, autophagy, pyroptosis, ferroptosis, efferocytosis — as drivers of spermatogenic failure
Targeting Programmed Cell Death in Male Infertility: Pathogenic Mechanisms and Therapeutic Strategies male infertility spermatogenesis autophagy oxidative stress narrative review inflammation
- A Third Way Sperm Cells Die: Ferroptosis2026-05
Review maps three oxidative stress-driven cell death pathways in testicular tissue, spotlighting ferroptosis as an understudied mechanism
Oxidative Stress-Related Programmed Cell Death in Male Infertility: Focussing on Ferroptosis male infertility oxidative stress spermatogenesis narrative review iron metabolism autophagy
- One Gene Variant Ties Infertility, Ataxia, and Brain Cell Death2026-04-22
RNF216 loss-of-function variants kill cells via runaway autophagy — found in 2 of 1,476 HH patients
RNF216 Variants Found in Patients With Dementia, Hypogonadotropic Hypogonadism, and Severe Ataxia Deregulate Autophagy genetics hypogonadism neurodegenerative diseases autophagy
- The Cell-Recycling Process Tied to Broken Sperm2026-01-20
A review of animal and lab data argues autophagy imbalance may drive low sperm count and motility, no new evidence
A narrative review on the role of autophagy in male infertility-associated sperm abnormalities autophagy male infertility spermatogenesis narrative review