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Science journalism, not medical advice.
Lab-Grown Mini-Testes Make Hormones — Sperm Still Elusive
2026-05-06
Testicular organoids sustain testosterone and inhibin B production for up to 12 weeks in culture, but complete spermatogenesis remains out of reach
Generation and Utility of Endocrine Functional Testicular Organoids
stem cells
spermatogenesis
male infertility
narrative review
testicular disease
Three Mouse Studies Don't Make a Therapy
2026-03-31
A systematic review of exactly 3 mouse studies concludes fat-cell secretions partially regenerate chemotherapy-damaged testes — in rodents
Adipose-Derived Mesenchymal Stem Cell Secretome Promotes Testicular Regeneration Following Chemically Induced Injury: A Review of Preclinical Studies
male infertility
stem cells
animal study
spermatogenesis
Lab-Grown Sperm: Closer, But Not There
2026-03-01
Narrative review maps iPSC-to-sperm progress — validated precursor cells exist, but maturation to functional sperm remains unsolved
The road to restore male fertility using in vitro-derived germ cells
male infertility
infertility
genetics
stem cells
Nanoparticles Sneak ATP Past the Testicular Wall
2025-10-13
ATP-loaded nanoparticles crossed the testicular barrier in mice and improved sperm motility — no human data yet
Blood-Testis Barrier-Crossing Extracellular Vesicles for Asthenozoospermia Therapy via Synergistic ATP Replenishment and Ferroptosis Suppression
male infertility
spermatogenesis
stem cells
oxidative stress
animal study
Sickle Cell Damages Sperm — So Does the Treatment
2025-05-30
Systematic review finds SCD impairs sperm parameters, and both hydroxyurea and stem cell transplant make it worse
Reproductive function and sperm parameters in men with sickle cell disease: a systematic review
male infertility
semen quality
genetics
stem cells
male infertility
96
sexual dysfunction
64
erectile dysfunction
58
surgical outcomes
53
biomarkers
47
evidence quality
44
spermatogenesis
43
genetics
43
animal study
40
semen quality
37
narrative review
35
women's health
34
oxidative stress
33
kidney stones
32
meta-analysis
29
cross-sectional
28
hypogonadism
26
infertility
26
testicular cancer
25
systematic review
24
health services
22
pediatric urology
19
environmental exposure
17
testosterone
16
survivorship
16
immunology
14
inflammation
14
vascular health
14
penile prosthesis
13
cohort study
13
obesity
12
testicular disease
12
pathology
12
traditional chinese medicine
12
penile cancer
12
metabolic syndrome
11
genomics
11
pelvic floor
10
hypospadias
9
screening
9
prostate cancer
9
epidemiology
8
testosterone therapy
8
cardiovascular disease
8
case report
8
pregnancy
7
antidepressants
7
retrospective cohort
6
quality of life
6
pharmacovigilance
6
epigenetics
6
stem cells
5
urinary incontinence
5
cryptorchidism
5
diabetes
4
robotics
4
antisperm antibodies
4
mental health
3
scoping review
3
BPH
3
patient satisfaction
3
neurodegenerative diseases
3
menopause
3
iron metabolism
3
sperm capacitation
3
varicocele
3
case-control study
3
HPV
3
DNA fragmentation
3
gut microbiome
2
autophagy
2
artificial intelligence
2
Peyronie's disease
2
Parkinson's disease
2
multiple sclerosis
2
antipsychotics
2
contraception
2
air pollution
2
paraneoplastic syndrome
1
exercise
1
tuberculosis
1
nanomedicine
1
spinal cord injury
1
occupational exposure
1
premature ejaculation
1
COVID-19
1
anabolic steroids
1
HIV
1
kidney cancer
1
bladder exstrophy
1
longitudinal study
1
relationship health
1
vaginismus
1