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· stem cells (6)
Science journalism, not medical advice.
Shockwave, PRP, Stem Cells: Still Not Proven
2026-06-05
ISSM-commissioned review of 36 studies finds mixed, inconsistent evidence for all restorative ED therapies, with 78% of trials failing to report clinically meaningful outcomes
Systematic Review on the Safety and Effectiveness of Restorative Therapies for Erectile Dysfunction
erectile dysfunction
systematic review
evidence quality
stem cells
Lab-Grown Mini-Testes Make Hormones — Sperm Still Elusive
2026-05-06
Testicular organoids sustain testosterone and inhibin B production for up to 12 weeks in culture, but complete spermatogenesis remains out of reach
Generation and Utility of Endocrine Functional Testicular Organoids
stem cells
spermatogenesis
male infertility
narrative review
testicular disease
Three Mouse Studies Don't Make a Therapy
2026-03-31
A systematic review of exactly 3 mouse studies concludes fat-cell secretions partially regenerate chemotherapy-damaged testes — in rodents
Adipose-Derived Mesenchymal Stem Cell Secretome Promotes Testicular Regeneration Following Chemically Induced Injury: A Review of Preclinical Studies
male infertility
stem cells
animal study
spermatogenesis
Lab-Grown Sperm: Closer, But Not There
2026-03-01
Narrative review maps iPSC-to-sperm progress — validated precursor cells exist, but maturation to functional sperm remains unsolved
The road to restore male fertility using in vitro-derived germ cells
male infertility
infertility
genetics
stem cells
Nanoparticles Sneak ATP Past the Testicular Wall
2025-10-13
ATP-loaded nanoparticles crossed the testicular barrier in mice and improved sperm motility — no human data yet
Blood-Testis Barrier-Crossing Extracellular Vesicles for Asthenozoospermia Therapy via Synergistic ATP Replenishment and Ferroptosis Suppression
male infertility
spermatogenesis
stem cells
oxidative stress
animal study
Sickle Cell Damages Sperm — So Does the Treatment
2025-05-30
Systematic review finds SCD impairs sperm parameters, and both hydroxyurea and stem cell transplant make it worse
Reproductive function and sperm parameters in men with sickle cell disease: a systematic review
male infertility
semen quality
genetics
stem cells
male infertility
137
erectile dysfunction
91
sexual dysfunction
85
narrative review
78
surgical outcomes
71
biomarkers
66
animal study
62
genetics
58
spermatogenesis
58
evidence quality
57
oxidative stress
52
women's health
46
hypogonadism
45
kidney stones
42
semen quality
41
meta-analysis
38
cross-sectional
38
systematic review
38
infertility
33
testicular cancer
33
health services
33
pediatric urology
30
testosterone
25
survivorship
22
inflammation
22
environmental exposure
20
immunology
19
pathology
19
vascular health
18
obesity
18
quality of life
18
penile cancer
18
prostate cancer
17
cohort study
17
testicular disease
17
retrospective cohort
17
testosterone therapy
16
epidemiology
16
genomics
16
traditional chinese medicine
16
cardiovascular disease
15
penile prosthesis
15
case report
14
metabolic syndrome
13
pelvic floor
13
pregnancy
11
hypospadias
11
screening
11
diabetes
10
mental health
9
pharmacovigilance
8
epigenetics
8
varicocele
8
antidepressants
8
cryptorchidism
8
menopause
7
nanomedicine
6
HPV
6
stem cells
6
gut microbiome
5
robotics
5
case-control study
5
BPH
5
patient satisfaction
5
DNA fragmentation
5
urinary incontinence
5
artificial intelligence
5
exercise
4
cancer survivors
4
hypertension
4
autophagy
4
Peyronie's disease
4
scoping review
4
antisperm antibodies
4
multiple sclerosis
3
relationship health
3
longitudinal study
3
priapism
3
neurodegenerative diseases
3
iron metabolism
3
sperm capacitation
3
bibliometrics
2
occupational exposure
2
chronic kidney disease
2
Parkinson's disease
2
antipsychotics
2
kidney cancer
2
contraception
2
spinal cord injury
2
premature ejaculation
2
air pollution
2
stress
1
couples therapy
1
dietary exposure
1
circadian rhythm
1
emergency medicine
1
paraneoplastic syndrome
1
orchitis
1
tuberculosis
1
COVID-19
1
opioids
1
anabolic steroids
1
HIV
1
neurostimulation
1
bladder exstrophy
1
vaginismus
1