← all papers · retrospective cohort (17) Science journalism, not medical advice.
- 1 in 4 NOA Men Become Fathers via TESE2026-06-20
Only 40 of 168 men with severe infertility fathered a child via TESE-ICSI, taking a median 19.5 months
Cumulative live birth rates following testicular sperm extraction in non-obstructive male infertility. male infertility retrospective cohort pregnancy surgical outcomes
- Two Hormones Beat One for Azoospermic Men2026-06-16
74% of azoospermic men produced sperm on hormone therapy; combination outperformed monotherapy 78% vs 33%
Therapeutic Benefits of Gonadotropins in Male Hypogonadotropic Hypogonadism hypogonadism male infertility spermatogenesis retrospective cohort pregnancy
- Hair Drug Users Take ED Pills 8 Months Earlier2026-06-08
Men on finasteride 1mg for hair loss were prescribed PDE5 inhibitors at 13.6% vs 10.5% — and 238 days sooner
The Urologic Impact of Long-Term Finasteride 1-mg Use for Androgenic Alopecia: A Matched-Cohort Database Analysis erectile dysfunction BPH prostate cancer retrospective cohort pharmacovigilance
- Bile Pigment Spotted Where Kidney Stones Form2026-06-04
Red-orange crystals in 1.1% of Randall's plaque stones were identified as calcium bilirubinate — a bile pigment — possibly linked to liver disease.
Calcium Bilirubinate at the Randall's Plaque-Kidney Stone Interface: First Description kidney stones pathology retrospective cohort case report
- When Testicular Cancer Attacks the Brain2026-05-29
Anti-KLHL11 encephalitis is rare, lethal in 1 of 3 patients within a year, and linked to seminoma in nearly a third of cases.
Clinical Manifestations, Tumor Associations, and Long-Term Outcomes of Anti-KLHL11 Encephalitis testicular cancer immunology paraneoplastic syndrome retrospective cohort
- Brain Tumors Trigger Both Early and Late Puberty2026-05-19
In 60 kids with intracranial germ cell tumors, 45% developed a puberty disorder—too early, too late, or both in sequence
Pubertal Dysfunctions in Intracranial Germ Cell Tumors hypogonadism pediatric urology retrospective cohort survivorship
- Penile Implant Drains: Trend Toward Worse, Not Better2026-05-11
Drain use after three-piece penile implant surgery showed no benefit — hematoma rates trended slightly higher in the drain group
Does a 24-h Closed-Suction Drain Reduce Infection and Hematoma After Inflatable Penile Prosthesis Surgery? A Comparative Study penile prosthesis surgical outcomes erectile dysfunction retrospective cohort
- Young Men With ED Almost Never See a Psychiatrist2026-05-11
In a cohort of young men with ED and a diagnosed mental health condition, only 6.2% ever had a psychiatry appointment.
Evaluating Mental Health Risk and Psychiatric Care Access in 18–40 Year Old Men with Erectile Dysfunction erectile dysfunction mental health health services retrospective cohort
- Burned-Out Testis After Chemo Rarely Hides Viable Tumor2026-04-03
After chemo for metastatic testicular cancer, no viable invasive tumor was found in men whose post-chemo ultrasound showed normal, burned-out, or sub-centimeter residual findings.
Postchemotherapy Orchiectomy in Metastatic Testicular Germ Cell Tumors: Pathologic Findings and Predictors of Residual Viable Disease testicular cancer pathology surgical outcomes retrospective cohort
- Clear Guidelines Aren't Enough to Close the Rural Gap2026-03-31
Rural U.S. patients with early-stage kidney and prostate cancer were up to 26% less likely to receive guideline-concordant care than urban patients
Rural-Urban Variation in Guideline-Concordant Management of Early-Stage Kidney, Prostate, and Testicular Cancer in the United States (2010–2022) kidney cancer prostate cancer testicular cancer health services epidemiology surgical outcomes retrospective cohort
- Old Prostate Exam Survives the MRI Era2026-03-03
A 164-patient retrospective found suspicious DRE was present in 48.5% of clinically significant prostate cancer cases and correlated with advanced pathological stage (≥pT3)
In the Era of mpMRI and PSMA PET/CT: Does Digital Rectal Examination Still Matter? prostate cancer screening retrospective cohort surgical outcomes biomarkers
- Vanished Testicles Rarely Harbor Cancer Risk2026-02-14
In 262 boys with absent testes, only 1.1% of remnants contained viable germ cells — and no malignancy was found in 15 years.
Testicular Regression Syndrome Revisited: Insights from a 15-Year Retrospective Study and Evolving Perspectives on Management pediatric urology cryptorchidism testicular disease surgical outcomes retrospective cohort
- One Mouth Graft, Near-Zero Failures in Pediatric Urethral Repair2026-02-04
Lip mucosa grafted dorsally onto the urethra cut stricture recurrence to 4.5% over a median 6-year follow-up in 22 boys
Dorsal Onlay Oral Mucosa (DOOM) Urethroplasty for Post-Hypospadias Stricture hypospadias pediatric urology surgical outcomes retrospective cohort
- Sertoli vs. Leydig: New Marker, Tiny Sample2026-02-03
LEF1 stained positive in all 5 Sertoli cell tumors and zero of 12 Leydig cell tumors — promising signal, absurdly small dataset
LEF1 and IL13RA2 in Testicular Sex Cord-Stromal Tumors: LEF1 as a Potential Diagnostic Marker for Sertoli Cell Tumors testicular cancer pathology biomarkers retrospective cohort
- Varicocele Surgery Rescues Sperm in Half of Near-Zero Cases2026-01-21
54% of men with cryptozoospermia (near-zero sperm) improved to at least oligozoospermia after varicocele repair in a 24-man study
Semen Parameter Response to Varicocele Repair in Infertile Men With Cryptozoospermia varicocele male infertility semen quality surgical outcomes retrospective cohort
- Only 12% of Men Satisfied With Surgical Appearance2025-12-26
Only 12% of men with repaired bladder exstrophy were satisfied with genital appearance; 43% of women met criteria for sexual dysfunction
Long-term Sexual Outcomes in Classic Bladder Exstrophy: Insights from Standardized Scores bladder exstrophy pediatric urology sexual dysfunction erectile dysfunction surgical outcomes patient satisfaction retrospective cohort quality of life
- A New Heart Helps Your Sex Life. A New Pancreas Doesn't.2025-07-08
Transplantation linked to a 2.11% absolute drop in coded sexual dysfunction in men — statistically real, clinically modest
The Impact of Solid Organ Transplantation on Sexual Dysfunction and Infertility in Older Men and Women: A Claims-Based Study sexual dysfunction erectile dysfunction infertility retrospective cohort health services surgical outcomes