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← all papers · pharmacovigilance (8) Science journalism, not medical advice.

Hair Drug Users Take ED Pills 8 Months Earlier2026-06-08
Men on finasteride 1mg for hair loss were prescribed PDE5 inhibitors at 13.6% vs 10.5% — and 238 days sooner
The Urologic Impact of Long-Term Finasteride 1-mg Use for Androgenic Alopecia: A Matched-Cohort Database Analysis erectile dysfunction BPH prostate cancer retrospective cohort pharmacovigilance
Sildenafil Wins — But Viatris Paid For It2026-06-05
Network meta-analysis of 83 RCTs finds sildenafil 100mg has the highest odds ratio (9.06) vs placebo — funded by sildenafil's manufacturer
A Comparative Evaluation of On-Demand Phosphodiesterase-5 Inhibitor Efficacy in Erectile Dysfunction Treatment: A Systematic Review and Network Meta-Analysis of Double-Blind, Placebo-Controlled, Randomized Trials erectile dysfunction systematic review meta-analysis pharmacovigilance
CML Drug Hits Developing Testes Hardest2026-05-14
Imatinib damages testes via c-KIT/PDGFR inhibition; neonatal exposure carries high irreversibility risk, adult exposure is more forgiving
A Scoping Review of Imatinib-Induced Testicular Toxicity and Male Fertility Impairment male infertility spermatogenesis scoping review pharmacovigilance pediatric urology
Pharma Authors Write Fictional Stories, Call It Evidence2026-04-02
Two of four authors work for Viatris — a PDE5i manufacturer — yet COI is listed as "not listed"
Narrative-Based Sexual Medicine: Clinical Vignettes and PDE5 Inhibitor Management in Real-World ED erectile dysfunction evidence quality pharmacovigilance
Your Antipsychotic Determines Which Sexual Side Effect You Get2026-03-07
Aripiprazole flagged for compulsive sexual behavior (ROR: 296.23); risperidone and paliperidone linked to decreased libido and anorgasmia — signals vary sharply by drug
Female Sexual Dysfunction Induced by Second-Generation Antipsychotic Drugs — A Disproportionality Analysis Based on the FAERS Database sexual dysfunction women's health antipsychotics pharmacovigilance
Which SSRI Hits Male Sexual Function Hardest?2026-02-07
Escitalopram and citalopram showed the strongest ED signals (ROR ~8) across 6.6 million FAERS reports; fluvoxamine's signal didn't reach significance
Male Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitors (SSRIs): A Pharmacovigilance Disproportionality Analysis of FAERS Data antidepressants erectile dysfunction pharmacovigilance sexual dysfunction
Sildenafil Beats Tadalafil—But Read the Fine Print2025-11-19
Sildenafil scored higher than tadalafil on satisfaction and hardness in 132,100 real-world patients; vardenafil had the worst side-effect profile (47.4% vs ~34%).
Head-to-head Comparison of the Safety and Efficacy Profiles of Three Phosphodiesterase Type 5 Inhibitors through Patient-reported Outcomes of 130 000 Patients from a Direct-to-consumer Platform Database erectile dysfunction pharmacovigilance health services evidence quality
Venlafaxine Nearly Doubles Sexual Dysfunction Risk in Depressed Men2025-11-08
Venlafaxine raised sexual dysfunction risk 27% vs citalopram overall — and 93% higher among hospitalized depression patients
Sexual Dysfunction in Male Patients After Initiating Treatment with Antidepressants antidepressants sexual dysfunction pharmacovigilance cohort study