← all papers · testicular disease (17) Science journalism, not medical advice.
- Meet the Immune Cells Guarding Your Sperm Supply2026-06-23
A review of mouse studies argues rogue immune cells in the testis may drive some male infertility
Testicular macrophages: core immune regulators and emerging therapeutic targets in spermatogenic dysfunction male infertility spermatogenesis immunology testicular disease animal study narrative review
- The Testicular Tumor That Fools Every Blood Test2026-06-19
A 21-year-old's painless testicular mass turned out to be a tumor type so rare it accounts for under 1% of testicular neoplasms — and all standard tumor markers came back normal.
Primary Testicular Neuroendocrine Tumor: Diagnostic Challenges and WHO 2022 Classification Insights case report testicular cancer testicular disease pathology biomarkers
- Two Supplements Blunt Chemo's Testicular Damage — In Rats2026-05-21
Melatonin and apigenin each partially reversed paclitaxel-induced testicular damage in rats, raising Johnsen scores from 5 back to ~8 out of 9
Comparative Protective Effects of Melatonin and Apigenin Against Paclitaxel-Induced Testicular Injury in Rats: Oxidative Stress, DNA Damage, Apoptosis, and NF-κB Signaling animal study oxidative stress spermatogenesis testicular disease male infertility
- The Testicular Tumors That Fool Even Pathologists2026-05-17
10% of testicular sex cord stromal tumors follow an aggressive, therapy-resistant course that can rapidly become fatal
Testicular Sex Cord Stromal Tumors testicular cancer testicular disease pathology narrative review
- Lab-Grown Mini-Testes Make Hormones — Sperm Still Elusive2026-05-06
Testicular organoids sustain testosterone and inhibin B production for up to 12 weeks in culture, but complete spermatogenesis remains out of reach
Generation and Utility of Endocrine Functional Testicular Organoids stem cells spermatogenesis male infertility narrative review testicular disease
- Testicular Calcifications Are Only Scary With Baggage2026-04-15
65 studies reviewed: isolated testicular microlithiasis carries minimal cancer risk on its own — the company it keeps is what matters
From Incidentaloma to Actionable Insight: A Clinical-Molecular-Imaging Framework for Risk-Stratified Management of Testicular Microlithiasis testicular cancer testicular disease scoping review biomarkers screening
- One Surgeon's Opinion Dressed Up as a Literature Review2026-03-12
A "comprehensive" review of varicocele surgery for testicle pain ends in personal opinion, not pooled data
Varicocele repair for chronic orchialgia varicocele testicular disease narrative review evidence quality
- The Testicular "Heart Attack" That Wasn't Torsion2026-02-27
A single case of segmental testicular infarction resolved with heparin — no surgery, no orchiectomy
Segmental Testicular Infarction: A Case Report testicular disease case report
- Vanished Testicles Rarely Harbor Cancer Risk2026-02-14
In 262 boys with absent testes, only 1.1% of remnants contained viable germ cells — and no malignancy was found in 15 years.
Testicular Regression Syndrome Revisited: Insights from a 15-Year Retrospective Study and Evolving Perspectives on Management pediatric urology cryptorchidism testicular disease surgical outcomes retrospective cohort
- Scrotal Calcifications Don't Trigger Immune Attack2026-02-06
In 1,755 infertile men, testicular microlithiasis was not associated with higher antisperm antibody rates (1.2% vs 3.5%, p=0.17)
Testicular Immune Privilege Maintained in Incidental Testicular Microlithiasis: Evidence from 1755 Infertile Men testicular disease infertility immunology semen quality
- Ultrasound Pattern Could Spare Testicles From Surgery2026-02-06
17 men with testicular sarcoidosis had tiny, stable nodules that mimicked cancer on ultrasound
Multiparametric Ultrasound Findings of Testicular Sarcoidosis testicular disease case report pathology testicular cancer
- Rare Testicular Tumors Get Diagnostic Clarity2026-01-26
Review maps how BAP1 and MTAP immunostaining now separate benign from malignant mesothelial lesions of the tunica vaginalis
Mesothelial Lesions of the Testis: A Review pathology testicular disease testicular cancer biomarkers
- Testicular Macrophages Do More Than We Thought2026-01-21
Review maps macrophage roles in testicular disease but produces no original data
Decoding mechanisms and therapeutic opportunities in testicular development diseases through macrophage immunology testicular disease immunology
- Rare Scrotal Cyst Mistaken for Tumor, Costs a Testicle2026-01-19
Meconium periorchitis — a sterile scrotal mass affecting 1 in 30,000 newborns — is routinely misdiagnosed as teratoma, potentially driving unnecessary orchiectomy
Meconium Periorchitis case report pediatric urology testicular disease pathology
- Intraoperative Biopsy Saved 81 Testes From Unnecessary Removal2025-11-20
Frozen section biopsy correctly identified 58% of small testicular masses as benign, sparing those patients radical orchidectomy — with zero false negatives across 135 cases.
Testicular Mass Frozen Section Examination: Pathological Insights and Diagnostic Accuracy testicular cancer testicular disease surgical outcomes pathology
- When the "Tumor" Was Just Misplaced Spleen2025-11-17
A 10-year-old's para-testicular "tumors" turned out to be ectopic splenic tissue — a rare anomaly that can prevent unnecessary surgery if recognized
An Unexpected Bond: Unraveling a Case of Spleno-Gonadal Fusion Anomaly Mistaken for Lymph Node and Testicular Tumor case report cryptorchidism pediatric urology testicular disease pathology
- CoQ10 Cuts Varicocele Damage — In Rats2025-10-07
CoQ10 reduced oxidative stress and improved sperm parameters in rat varicocele and hypoxia models via the caspase1-IL1β-egr2 pathway
Ameliorative Effects of Coenzyme Q10 Against Hypoxia-Induced and Varicocele-Associated Spermatogenesis Dysfunction in Rat animal study male infertility semen quality testicular disease