← all papers · testosterone therapy (16) Science journalism, not medical advice.
- Clomiphene Matches TRT's Testosterone Boost, Not Libido2026-07-11
Clomiphene raised testosterone about as well as TRT gel in 1,512 men, but libido scores came out lower
Clomiphene citrate versus testosterone replacement therapy in male hypogonadism: a systematic review of literature and meta-analysis hypogonadism testosterone therapy male infertility meta-analysis
- TRT and Heart Risk: Is a Gel Safer Than a Shot?2026-07-05
Low testosterone tracks with worse blood vessel markers, and TRT improves most of them, but gel vs. injection safety claims are still unproven
Circulating Markers of Cardiovascular Health in Hypogonadism Before and After Testosterone Therapy: Molecular Aspects and Formulation Comparison hypogonadism testosterone therapy cardiovascular disease vascular health biomarkers narrative review
- Female Testosterone Therapy: Only 2 Trials Back Premenopausal Use2026-07-03
Postmenopausal testosterone therapy has 7 RCTs behind it, premenopausal use has just 2
Testosterone therapy for female sexual dysfunction: a systematic review of the literature demonstrating outcomes in premenopausal and postmenopausal women testosterone therapy women's health sexual dysfunction systematic review menopause
- Testosterone After Prostate Cancer, Zero Recurrences2026-07-01
Testosterone restored sex drive in prostate cancer survivors, with zero recurrences in 136 men over 12 weeks
Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism: A Randomized Clinical Trial hypogonadism testosterone therapy prostate cancer cancer survivors
- 75% of Klinefelter Cases Go Undiagnosed2026-06-24
A review argues Klinefelter syndrome wrecks more than fertility, yet up to 75% of cases go undiagnosed
Klinefelter syndrome beyond hypogonadism: multisystem manifestations and a framework for clinical surveillance hypogonadism cardiovascular disease testosterone therapy narrative review
- Most Low Testosterone Is Just Obesity2026-06-23
JAMA review puts obesity-driven low T (2–8% prevalence) well ahead of true gonadal failure (<1%), with weight loss as first-line.
Adult Male Hypogonadism: A Review hypogonadism testosterone obesity testosterone therapy narrative review
- 1 in 5 Online Testosterone Clinics Invent Cardiovascular Benefits2026-05-19
253 testosterone clinic websites worldwide: 1 in 4 promote off-guideline treatments, 1 in 5 falsely claim cardiovascular benefits
Discordance Between Online Information and Male Hypogonadism Clinical Guidelines: A Global Multilingual Content Analysis hypogonadism testosterone therapy health services evidence quality
- Testosterone Therapy May Raise Fracture Risk2026-05-16
TRAVERSE trial found higher fracture rates in men randomized to testosterone — a result the review calls "unexpected"
Testosterone and Bone Health in Men testosterone testosterone therapy hypogonadism evidence quality
- Skipping Testosterone Therapy Raises Death Risk2026-04-22
In 408 men with pituitary tumors followed 8 years, TRT showed no increase in heart attack or stroke risk — but untreated low T was tied to higher mortality
Secondary Hypogonadism and Effects of Testosterone Replacement Therapy on Cardiovascular Events hypogonadism testosterone therapy cardiovascular disease cohort study
- FSH, Not Just Testosterone, May Drive Muscle Loss2026-03-17
Men with Klinefelter syndrome had significantly less lean mass than Kallmann men (ALMI 7.28 vs 8.37 kg/m²), implicating FSH
Body Composition by DXA in Patients with Klinefelter and Kallmann Syndrome: The Kama Study hypogonadism testosterone therapy genetics biomarkers
- Testosterone Rescues Muscle Loss on Tirzepatide2026-03-09
Adding TRT to tirzepatide in 5 non-responding men preserved lean mass and doubled physical activity at 6 months
Effects of Testosterone Undecanoate as Add-On Therapy in Obese Hypogonadal Men That Are Late Responders to Tirzepatide: A Pilot Study hypogonadism obesity testosterone therapy erectile dysfunction metabolic syndrome
- TRT: Lower Prostate Cancer, Higher BPH Risk2026-02-20
A Medicare study of 547K men found TRT linked to 16% lower prostate cancer hazard but 13% higher BPH risk
Association Between Testosterone Replacement Therapy and Prostatic Disorders in Elderly Hypogonadal Men hypogonadism prostate cancer BPH testosterone therapy
- It's Not Age That Tanks Testosterone2026-02-06
Review of current evidence finds aging alone doesn't cause low T — obesity and diabetes do, and recent RCTs report no added cardiovascular risk from treatment
Functional Testosterone Deficiency in Aging Men: Clinical Impact, Diagnostic Pathways, and Treatment Strategies hypogonadism testosterone therapy metabolic syndrome narrative review
- Three Specialties Finally Agree on Low T2026
Brazil's three major societies align on hypogonadism diagnosis and TRT — first multidisciplinary consensus for the country
Care of Patients with Male Hypogonadism: A Joint Position Statement from SBEM, SBU, and ABEMSS hypogonadism testosterone therapy metabolic syndrome obesity
- Surgery for Micropenis: Evidence Too Thin to Recommend2026
Narrative review of 36 studies: early testosterone therapy beats surgery for micropenis, but RCT data barely exists
Micropenis in Children and Adolescents: A Narrative Review hypogonadism testosterone therapy evidence quality pediatric urology
- Testosterone Review Skips the Hard Evidence2025-12-24
A non-systematic review says testosterone therapy is safe and effective, but cites no funding or conflicts
Testosterone Therapy in Adult Males with Hypogonadism testosterone therapy hypogonadism narrative review evidence quality