penisdoc.md

← all papers · pediatric urology (30) Science journalism, not medical advice.

Pediatric Penile Emergencies: Screen for Abuse2026-06-01
Narrative review covering ED diagnosis and management of pediatric penile conditions, from paraphimosis to strangulation injury, with abuse screening emphasized
Management of pediatric penile problems in the emergency department. pediatric urology narrative review health services emergency medicine
Brain Tumors Trigger Both Early and Late Puberty2026-05-19
In 60 kids with intracranial germ cell tumors, 45% developed a puberty disorder—too early, too late, or both in sequence
Pubertal Dysfunctions in Intracranial Germ Cell Tumors hypogonadism pediatric urology retrospective cohort survivorship
CML Drug Hits Developing Testes Hardest2026-05-14
Imatinib damages testes via c-KIT/PDGFR inhibition; neonatal exposure carries high irreversibility risk, adult exposure is more forgiving
A Scoping Review of Imatinib-Induced Testicular Toxicity and Male Fertility Impairment male infertility spermatogenesis scoping review pharmacovigilance pediatric urology
Modified Hypospadias Fix: Better Flow, Same Risk2026-05-11
Modified TIPU improved urinary flow rates and penile straightness scores at 2 years, with no increase in complication rates (n=183)
Efficacy of Modified Tubularized Incised Plate Urethroplasty for Hypospadias hypospadias pediatric urology surgical outcomes
Hypospadias Men Care About Looks, Not Meatus Location2026-05-11
78 of 501 patients responded: those who did reported good overall satisfaction, driven more by appearance than urinary function (r = .60)
Long-Term Sex Life After Hypospadias Repair: Appearance Beats Anatomy hypospadias surgical outcomes patient satisfaction pediatric urology sexual dysfunction quality of life
When Should Teen Varicoceles Get Surgery?2026-04-30
One children's hospital's playbook for deciding which teens with varicocele need surgery
Adolescent varicocele: a surgical conundrum varicocele pediatric urology male infertility narrative review surgical outcomes
Five Pregnancy Factors Predict Hypospadias Risk2026-04-27
Five obstetric factors — gestational hypertension, abnormal placenta, and preterm birth among them — predicted hypospadias with AUC 0.857 in temporal validation
Risk Factor Analysis and Nomogram Predictive Model Construction for Neonatal Hypospadias: A Large-Scale Multicenter Study in East China hypospadias pediatric urology pregnancy biomarkers
Hypospadias Hints at Hidden Testicular Problems2026-04-22
113 Danish infants with hypospadias showed reduced Sertoli and Leydig cell markers during minipuberty, regardless of defect severity
Reproductive Hormones During Minipuberty Suggest Subtle Testicular Impairments in Boys With Hypospadias hypospadias pediatric urology testosterone biomarkers
Female Fetal Ligaments Aren't Hormonally Passive2026-04-05
In first-trimester human fetuses, caudal genital ligaments in both sexes express receptors for androgens, estrogens, and INSL3 — the "passive female default" model doesn't hold in humans
Receptivity of the Human Male and Female Fetal Caudal Genital Ligament to Gonadal Hormones cryptorchidism pediatric urology environmental exposure pregnancy genomics
Infant Hormone Window Predicts Adult Fertility2026-03-26
Hormone levels at 1–3 months of life predict adult reproductive capacity and can flag hypogonadism before symptoms appear
Clinical Implications of Minipuberty pediatric urology hypogonadism biomarkers infertility
Every Common Kidney Stone Fix Has Weak Evidence2026-03-24
31-study review finds "low" strength-of-evidence for nearly every kidney stone prevention strategy, and zero data on surveillance imaging
Prevention of Recurrent Nephrolithiasis in Adults and Children: A Systematic Review kidney stones systematic review evidence quality pediatric urology
A Body Measurement Tracks Hypospadias Severity2026-03-21
Boys with hypospadias have shorter anogenital distance (SMD −1.24), with the gap widening as severity increases across 6,905 infants
Association Between Anogenital Distance and Hypospadias: A Systematic Review and Meta-Analysis hypospadias meta-analysis pediatric urology biomarkers environmental exposure
75,000 Exams to Find One Testicular Cancer2026-03-17
Screening 300,793 adolescents caught 4 testicular cancers in 6 months — and 86% of all cases were stage I anyway
Screening of Adolescents for Testicular Cancer — A Nationwide Retrospective Cohort Study screening testicular cancer cohort study pediatric urology
51% Needed Reoperations — 97% Still Don't Regret It2026-03-12
Half of patients required unplanned reoperations; only 2.9% of adolescents later reported decisional regret about early surgery.
Adolescent Satisfaction and Decisional Regret After Hypospadias Repair in Early Childhood hypospadias pediatric urology surgical outcomes patient satisfaction
In Cryptorchidism, the Support Cells Fail First2026-03-07
In a mouse cryptorchidism model, Sertoli and peritubular myoid cells show stress signals within 3 days — before germ cells begin dying
Somatic Cell Dysfunction Precedes Testicular Degeneration in a Surgical Model of Cryptorchidism cryptorchidism animal study pediatric urology spermatogenesis
When a Boy's Anatomy Needs Genetic Answers First2026-03-04
In 43 children with proximal hypospadias, every patient had severe ventral chordee and most had an underlying disorder of sex development requiring workup before surgery
In Which Cases of Proximal Hypospadias Detailed Investigations Are Necessary pediatric urology cryptorchidism surgical outcomes hypospadias
Vanished Testicles Rarely Harbor Cancer Risk2026-02-14
In 262 boys with absent testes, only 1.1% of remnants contained viable germ cells — and no malignancy was found in 15 years.
Testicular Regression Syndrome Revisited: Insights from a 15-Year Retrospective Study and Evolving Perspectives on Management pediatric urology cryptorchidism testicular disease surgical outcomes retrospective cohort
One Mouth Graft, Near-Zero Failures in Pediatric Urethral Repair2026-02-04
Lip mucosa grafted dorsally onto the urethra cut stricture recurrence to 4.5% over a median 6-year follow-up in 22 boys
Dorsal Onlay Oral Mucosa (DOOM) Urethroplasty for Post-Hypospadias Stricture hypospadias pediatric urology surgical outcomes retrospective cohort
Childhood Obesity Shrinks Testicles Before Puberty Starts2026-01-27
Obese prepubertal boys had smaller testicular volume, shorter penis length, and lower testosterone than normal-weight peers in a 60-boy study.
Obesity Impairs Male Reproductive Development in Prepubertal Boys via Local Adipose Tissue Inflammation and the STAT3/CYP19A1 Pathway obesity male infertility testosterone pediatric urology inflammation animal study
Rare Scrotal Cyst Mistaken for Tumor, Costs a Testicle2026-01-19
Meconium periorchitis — a sterile scrotal mass affecting 1 in 30,000 newborns — is routinely misdiagnosed as teratoma, potentially driving unnecessary orchiectomy
Meconium Periorchitis case report pediatric urology testicular disease pathology
Three Cuts, 99% Straight: A Severe Hypospadias Series2026-01-13
Three ventral corporotomies alone corrected penile curvature in 81% of cases; adding one dorsal plication pushed success to 99% across 400 patients
Efficacy of Three Corporotomies to Correct Ventral Penile Curvature in 400 Patients With Severe Hypospadias hypospadias pediatric urology surgical outcomes
Hypospadias Surgeons Admit They're Undertrained2026-01-12
103 surveyed surgeons reported a gap between the case volume needed for competency and what residency actually delivers
Education and Training in Hypospadias Surgery: Current Status, Competency Assessment, and the Role of Modern Educational Tools hypospadias pediatric urology surgical outcomes health services
New Lab Bench for a Rare Childhood Testicular Cancer2026-01-12
First PDX model for pediatric testicular yolk sac tumor, validated against a 109-patient retrospective series; 91.7% of patients presented at stage I
Establishment and Characterization of a Testicular Yolk Sac Tumor PDX Model testicular cancer pediatric urology animal study surgical outcomes
Surgery for Micropenis: Evidence Too Thin to Recommend2026
Narrative review of 36 studies: early testosterone therapy beats surgery for micropenis, but RCT data barely exists
Micropenis in Children and Adolescents: A Narrative Review hypogonadism testosterone therapy evidence quality pediatric urology
Only 12% of Men Satisfied With Surgical Appearance2025-12-26
Only 12% of men with repaired bladder exstrophy were satisfied with genital appearance; 43% of women met criteria for sexual dysfunction
Long-term Sexual Outcomes in Classic Bladder Exstrophy: Insights from Standardized Scores bladder exstrophy pediatric urology sexual dysfunction erectile dysfunction surgical outcomes patient satisfaction retrospective cohort quality of life
When the "Tumor" Was Just Misplaced Spleen2025-11-17
A 10-year-old's para-testicular "tumors" turned out to be ectopic splenic tissue — a rare anomaly that can prevent unnecessary surgery if recognized
An Unexpected Bond: Unraveling a Case of Spleno-Gonadal Fusion Anomaly Mistaken for Lymph Node and Testicular Tumor case report cryptorchidism pediatric urology testicular disease pathology
Uterus in Males: A Hidden Infertility Cause2025-11-07
Only 1 in 5 men with PMDS have conceived naturally at time of diagnosis; most present with cryptorchidism or hernias
Persistent Müllerian Duct Syndrome - A Rare but Important Cause of Male Factor Infertility cryptorchidism male infertility narrative review pediatric urology
Older Mothers, More Severe Hypospadias: Small Study2025-07-15
Boys with hypospadias had shorter anogenital distance (4.64 vs 5.33 cm); maternal age ≥34 correlated with severe cases
Genetic Susceptibility and Pathogenesis of Hypospadias hypospadias pediatric urology case-control study genetics
After Hirschsprung Surgery, the Bowel Predicts ED2024-12-23
Nordic men who had pull-through surgery for Hirschsprung disease reported 12.7% failure to conceive — below the WHO population estimate of 16.5%
Fertility and Sexual Function in Males With Hirschsprung Disease: A Nordic Cross-sectional Study cross-sectional erectile dysfunction male infertility pediatric urology surgical outcomes quality of life
A Penile Erection Lasting 4+ Hours Is an Emergency in Kids Too2024-11-25
Sickle cell disease is the leading cause of priapism in boys, and delayed treatment risks permanent erectile dysfunction
Priapism in the paediatric and adolescent population pediatric urology priapism erectile dysfunction narrative review