← all papers · testicular cancer (33) Science journalism, not medical advice.
- Robotic Testis Cancer Surgery: One Country, One Hospital2026-06-22
A 20-year literature map of robotic RPLND finds 93 total papers, nearly 40% from the US, with Johns Hopkins alone matching the output of every other institution.
Research trends and collaboration patterns in robotic retroperitoneal lymph node dissection for testicular cancer testicular cancer robotics surgical outcomes bibliometrics
- The Testicular Tumor That Fools Every Blood Test2026-06-19
A 21-year-old's painless testicular mass turned out to be a tumor type so rare it accounts for under 1% of testicular neoplasms — and all standard tumor markers came back normal.
Primary Testicular Neuroendocrine Tumor: Diagnostic Challenges and WHO 2022 Classification Insights case report testicular cancer testicular disease pathology biomarkers
- Why Won't Testicular Cancer Respond to Immunotherapy?2026-06-11
Checkpoint inhibitors largely fail in testicular germ cell tumors despite PD-L1 expression and tumor-infiltrating lymphocytes — a review argues miRNAs may explain why
MicroRNAs and Immunotherapy in Testicular Germ Cell Tumors: Opportunities and Challenges for Modulation of the Immune Microenvironment testicular cancer immunology biomarkers narrative review
- When Testicular Cancer Attacks the Brain2026-05-29
Anti-KLHL11 encephalitis is rare, lethal in 1 of 3 patients within a year, and linked to seminoma in nearly a third of cases.
Clinical Manifestations, Tumor Associations, and Long-Term Outcomes of Anti-KLHL11 Encephalitis testicular cancer immunology paraneoplastic syndrome retrospective cohort
- The Testicular Tumors That Fool Even Pathologists2026-05-17
10% of testicular sex cord stromal tumors follow an aggressive, therapy-resistant course that can rapidly become fatal
Testicular Sex Cord Stromal Tumors testicular cancer testicular disease pathology narrative review
- Curable Cancer That Still Kills Young Men2026-05-14
Testicular cancer is among the most curable metastatic solid tumors — but the poor-risk subset still carries significant mortality in young men
How to Optimize Treatment for Patients With Poor-Risk Testicular Cancer testicular cancer narrative review surgical outcomes survivorship
- Testicular Cancer Gets Its First Moderate-Risk Gene2026-05-06
CHEK2 becomes the first moderate-penetrance predisposition gene identified for testicular germ cell tumors, alongside growing ties to inherited cancer syndromes
Recent Advances in Genetic Predisposition to Primary Testicular Tumors testicular cancer genetics genomics narrative review
- Half of Cancer Survivors Can't Sleep. Nobody's Asking.2026-05-05
Commentary argues sleep disorders go unscreened in testicular cancer follow-up, citing a meta-analysis finding 60.7% prevalence of sleep disturbance across cancer survivors
Integrating the Relevance of Sleep into Testicular-Cancer Survivorship Care testicular cancer survivorship systematic review meta-analysis
- Testicular Cancer's Suicide Risk Lasts a Decade2026-04-15
Men with testicular cancer had 31% higher suicide mortality than the general population; risk doubled in year one and persisted for 10 years
Persistent Suicide Risk in Survivors of Testicular Cancer: A Population-Based Cohort Study testicular cancer survivorship cohort study epidemiology
- Testicular Calcifications Are Only Scary With Baggage2026-04-15
65 studies reviewed: isolated testicular microlithiasis carries minimal cancer risk on its own — the company it keeps is what matters
From Incidentaloma to Actionable Insight: A Clinical-Molecular-Imaging Framework for Risk-Stratified Management of Testicular Microlithiasis testicular cancer testicular disease scoping review biomarkers screening
- Malnutrition Splits Non-Seminoma Survival: 16% vs 97%2026-04-10
Non-seminoma patients with depleted metabolic profiles had 16.1% five-year survival vs 97.4% in those with preserved profiles
Metabolic Profile and Skeletal Muscle as Predictors of Survival in Testicular Germ Cell Tumors testicular cancer biomarkers survivorship cohort study
- Burned-Out Testis After Chemo Rarely Hides Viable Tumor2026-04-03
After chemo for metastatic testicular cancer, no viable invasive tumor was found in men whose post-chemo ultrasound showed normal, burned-out, or sub-centimeter residual findings.
Postchemotherapy Orchiectomy in Metastatic Testicular Germ Cell Tumors: Pathologic Findings and Predictors of Residual Viable Disease testicular cancer pathology surgical outcomes retrospective cohort
- Clear Guidelines Aren't Enough to Close the Rural Gap2026-03-31
Rural U.S. patients with early-stage kidney and prostate cancer were up to 26% less likely to receive guideline-concordant care than urban patients
Rural-Urban Variation in Guideline-Concordant Management of Early-Stage Kidney, Prostate, and Testicular Cancer in the United States (2010–2022) kidney cancer prostate cancer testicular cancer health services epidemiology surgical outcomes retrospective cohort
- Dog Tumor Marker Study Oversells Its Findings2026-03-31
87% of canine testicular seminomas expressed ezrin; higher expression correlated with the more invasive diffuse subtype (n=23)
Histomorphological Features and Ezrin Expression in Testicular Seminomas in Dogs: An Association with Potential Prognostic Value animal study testicular cancer pathology biomarkers
- Primary Care Penile Cancer Evidence: Coming Soon2026-03-30
A scoping review protocol — no findings yet — registering plans to map what evidence exists on these cancers in primary care
Strategies for Prevention, Early Detection and Management of Penile and Testicular Cancer in Primary Healthcare: Scoping Review Protocol penile cancer testicular cancer screening health services evidence quality
- The Testicular Tumor Hiding Behind Wrong Diagnoses2026-03-19
A review of an ultra-rare testicular malignancy, defined by EWSR1::ATF1 gene fusions, that has been routinely misclassified as other tumor types
Inflammatory and Nested Testicular Sex Cord Tumors: Clinical and Molecular Characterization testicular cancer genetics pathology biomarkers
- 75,000 Exams to Find One Testicular Cancer2026-03-17
Screening 300,793 adolescents caught 4 testicular cancers in 6 months — and 86% of all cases were stage I anyway
Screening of Adolescents for Testicular Cancer — A Nationwide Retrospective Cohort Study screening testicular cancer cohort study pediatric urology
- Combat Didn't Raise Cancer Risk. Infantry Did.2026-03-15
Infantry soldiers had twice the adjusted testicular cancer risk of other Army occupations — but combat deployment showed no association
Factors Associated With Testicular Cancer Risk Among New American Military Recruits During Wartime testicular cancer environmental exposure health services survivorship
- Welding May Triple Testicular Cancer Risk — But the Data Is Thin2026-03-14
Regular welders had a non-significant 2× elevated testicular cancer risk; non-seminoma risk tripled, but rests on very few cases
Risk of Testicular Cancer and Exposure to Welding Fumes testicular cancer environmental exposure occupational exposure case-control study
- Plastics at Birth, Testicular Cancer Later?2026-03-03
Newborn blood spots show phthalate mixtures at birth may predict testicular cancer decades later
Phthalates measured at birth and risk of testicular cancer in adolescents and young adults. testicular cancer environmental exposure
- Can Protein Tangles Kill Prostate Cancer Cells?2026-02-25
Review surveys disulfidptosis — a newly described cell death mechanism — as a theoretical target in prostate, testicular, and bladder cancer; no original data
Disulfidptosis and Androgenic Cancers: From Molecular Mechanisms to Clinical Applications and Future Translational Research prostate cancer testicular cancer pathology oxidative stress
- Blood Test Predicts Who Survives Salvage Chemo for Testicular Cancer2026-02-19
In relapsed germ cell tumors, a liquid biopsy tumor fraction above threshold predicted significantly worse OS; miR-371a-3p did not.
Impact of Circulating Tumor DNA and Copy-Number Alterations on Clinical Outcome in Relapsed/Refractory Germ Cell Tumors Treated With Salvage High-Dose Chemotherapy testicular cancer biomarkers genomics cohort study
- Cisplatin's Kidney Damage Cascades Into Heart Disease2026-02-13
41% of testicular cancer survivors had reduced kidney function a decade post-chemo; it cascades into hypertension, hyperlipidemia, and CVD
Renal Impairment and Late Toxicities Comparing Contemporary Chemotherapy Regimens for Testicular Cancer in a Real-World Setting testicular cancer survivorship cardiovascular disease vascular health
- Can a Blood Draw Replace Testicular Cancer Imaging?2026-02-11
Rising TGCT incidence, murky risk factors, and two emerging biomarkers — a military urology team surveys the field
Decoding testicular germ cell tumors: integrating risk, biology, and biomarkers into future care testicular cancer biomarkers genetics
- Ultrasound Pattern Could Spare Testicles From Surgery2026-02-06
17 men with testicular sarcoidosis had tiny, stable nodules that mimicked cancer on ultrasound
Multiparametric Ultrasound Findings of Testicular Sarcoidosis testicular disease case report pathology testicular cancer
- Sertoli vs. Leydig: New Marker, Tiny Sample2026-02-03
LEF1 stained positive in all 5 Sertoli cell tumors and zero of 12 Leydig cell tumors — promising signal, absurdly small dataset
LEF1 and IL13RA2 in Testicular Sex Cord-Stromal Tumors: LEF1 as a Potential Diagnostic Marker for Sertoli Cell Tumors testicular cancer pathology biomarkers retrospective cohort
- Rare Testicular Tumors Get Diagnostic Clarity2026-01-26
Review maps how BAP1 and MTAP immunostaining now separate benign from malignant mesothelial lesions of the tunica vaginalis
Mesothelial Lesions of the Testis: A Review pathology testicular disease testicular cancer biomarkers
- New Lab Bench for a Rare Childhood Testicular Cancer2026-01-12
First PDX model for pediatric testicular yolk sac tumor, validated against a 109-patient retrospective series; 91.7% of patients presented at stage I
Establishment and Characterization of a Testicular Yolk Sac Tumor PDX Model testicular cancer pediatric urology animal study surgical outcomes
- Two Genes Predict Penile Cancer Outcomes2026-01-05
A 2026 pathologist-facing review codifies how HPV status and TP53 mutations should shape penile cancer prognosis
Select Updates in Pathology of Kidney, Testis, and Penile Cancer for 2026 penile cancer testicular cancer kidney cancer pathology
- Intraoperative Biopsy Saved 81 Testes From Unnecessary Removal2025-11-20
Frozen section biopsy correctly identified 58% of small testicular masses as benign, sparing those patients radical orchidectomy — with zero false negatives across 135 cases.
Testicular Mass Frozen Section Examination: Pathological Insights and Diagnostic Accuracy testicular cancer testicular disease surgical outcomes pathology
- A Blood Test May Soon Detect Testicular Cancer2025-10-22
miR-371a-3p is approaching clinical use as a noninvasive diagnostic marker for testicular germ cell tumors
Testicular Germ Cell Tumors and Molecular Biomarkers testicular cancer biomarkers
- Testicular Cancer Is Getting Older and Surviving Better2025-10-13
30-year Spanish single-center data: men over 40 at diagnosis quadrupled from 7% to 29%, and 10-year cause-specific survival reached 97%
Epidemiological Patterns, Temporal Trends in Management and Long-Term Outcomes in Testicular Cancer: a 30-Year Single Center Experience testicular cancer survivorship cohort study health services
- Testicular Cancer Rehab: Big Claims, Thin Evidence2025-09-22
A review urging exercise and psych support for testicular cancer survivors despite admitting the evidence base is sparse
Exercise, diet and psychological support for patients with testicular cancer. testicular cancer survivorship