← all papers · sexual dysfunction (64) Science journalism, not medical advice.
- Insulin Pumps May Protect Female Sexual Function2026-05-28
About 1 in 3 women with T1DM has sexual dysfunction — twice the rate of healthy controls, and higher than T2DM
Female Sexual Dysfunction in Type 1 Diabetes: A Systematic Review and Meta-Analysis diabetes sexual dysfunction women's health meta-analysis systematic review
- Lupus Sexual Dysfunction: Body Image Is a Red Herring2026-05-23
In 68 Mexican women with lupus, overall body image did not predict sexual dysfunction — partner status, age, and self-esteem did
Body image and sexual function in women with systemic lupus erythematosus: a cross-sectional study sexual dysfunction cross-sectional women's health mental health quality of life
- BPH Drugs Tank Sex Drive. Does Rezum?2026-05-11
Rezum patients gained sexual desire and erectile function at 1 year; every drug regimen caused significant declines across multiple sexual domains
Sexual Function Outcomes of 5-Year Rezum Treatment vs. Drug Therapy for BPH BPH erectile dysfunction sexual dysfunction surgical outcomes
- Hypospadias Men Care About Looks, Not Meatus Location2026-05-11
78 of 501 patients responded: those who did reported good overall satisfaction, driven more by appearance than urinary function (r = .60)
Long-Term Sex Life After Hypospadias Repair: Appearance Beats Anatomy hypospadias surgical outcomes patient satisfaction pediatric urology sexual dysfunction quality of life
- New ED Drug: Higher Dose, Same Effect, More Side Effects2026-05-09
Phase 2 RCT of 255 men finds simenafil (5–20 mg) improves IIEF-EF scores ~9 points over placebo, but 20 mg hits 62% adverse event rate with no clear efficacy advantage over 5 mg
Efficacy and Safety of Simenafil in Men with Erectile Dysfunction: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group, Phase 2 Trial erectile dysfunction vascular health sexual dysfunction
- Exercise Boosts Female Sexual Function—Evidence Weak2026-05-09
Exercise interventions produced a mean 5.31-point FSFI improvement vs. controls (15 studies), but evidence certainty is rated low.
Systematic Review and Meta-Analysis on the Beneficial Effect of Exercise on Sexual Dysfunction in Women sexual dysfunction systematic review meta-analysis women's health pelvic floor evidence quality
- Female Sexual Dysfunction: Still Playing Catch-Up2026-05-07
Narrative review from Duke maps all 4 DSM-5 subtypes of female sexual dysfunction and finds evidence for multiple treatments—but measurement tools remain unstandardized
Female Sexual Dysfunction: Current Models and Treatment Options sexual dysfunction women's health narrative review pelvic floor
- Breast Cancer Therapy's Unspoken Sexual Toll2026-05-04
An integrative review of 43 studies found sexual dysfunction in 51–93% of breast cancer patients on endocrine therapy, yet providers routinely stay silent about it.
Sexual Health Among Patients With Breast Cancer Undergoing Endocrine Therapy: An Integrative Review sexual dysfunction women's health survivorship systematic review
- Lupus Roughly Doubles the Odds of Female Sexual Dysfunction2026-05-04
58.8% of lupus patients screen positive for FSD — 2.6x healthy controls, though extreme heterogeneity muddies the estimate
Prevalence of Female Sexual Dysfunction Among Women with Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis sexual dysfunction women's health immunology systematic review meta-analysis epidemiology
- The Psych Treatment That Works Isn't CBT2026-05-01
Overall effect looks strong (SMD=1.37), but CBT and mindfulness had near-zero effect — counseling and education drove the headline.
Psychological Treatments for Sexual Concerns in Perimenopausal and Postmenopausal Women: A Systematic Review and Meta-Analysis menopause women's health sexual dysfunction meta-analysis systematic review mental health
- Shockwave and PRP for ED? Still Experimental, Review Concludes2026-04-30
Narrative review synthesizes the full ED treatment ladder — prosthetics top 95% satisfaction; shockwave and PRP remain experimental.
Erectile Dysfunction: A Comprehensive Review of Pathophysiology, Diagnosis and Contemporary Management erectile dysfunction narrative review penile prosthesis sexual dysfunction evidence quality
- Robotic Surgery's Edge Over Laparoscopy? Basically Nothing2026-04-27
44 studies, 6,121 patients: robotic rectal surgery shows no consistent advantage over laparoscopy for urinary or sexual function
Comparison of Functional Outcomes Between Robotic and Laparoscopic Surgery in Rectal Cancer Patients: Systematic Review and Meta-Analysis surgical outcomes meta-analysis sexual dysfunction robotics
- 31 Studies, Still No Clear Answer2026-04-17
31 studies on UI and sexual function reviewed; inconsistent findings prevent any conclusions about what actually works
Strategies to Improve Sexual Health in Women with Urinary Incontinence: A Scoping Review urinary incontinence sexual dysfunction women's health pelvic floor scoping review
- Treating Rare Tumors Quietly Wrecks Fertility2026-04-15
Review finds chemotherapy has proven fertility harm in NET patients, while somatostatin analogues appear relatively safe — but data on sexual function is nearly absent
Reproductive and Sexual Sequelae of Neuroendocrine Tumour Therapies sexual dysfunction infertility survivorship systematic review
- Sling Surgery Lifts Sexual Function at 6 Months, Then Fades2026-04-09
MUS surgery improved PISQ-12 scores by 4.49 points at 6 months, but the gains largely reversed by 12 months and didn't recover
Impact of Mid-Urethral Sling Surgery on Sexual Function in Women with Stress Urinary Incontinence: A Meta-Analysis of Randomized Controlled Trials meta-analysis systematic review sexual dysfunction pelvic floor surgical outcomes women's health urinary incontinence
- Reddit Fills the Gap Pelvic Pain Doctors Left2026-04-09
201 Reddit posts reveal that pelvic pain patients turn online because medicine consistently fails to diagnose or validate their conditions
Seeking Answers and Finding Support: A Qualitative Analysis of Sexual and Pelvic Pain Online Communities on Reddit pelvic floor sexual dysfunction women's health health services
- Sensation Loss Predicts Penile Implant Satisfaction2026-04-09
After IPP surgery in 159 men, sensory loss predicted 17.7-point lower satisfaction scores; penoscrotal vs. infrapubic approach made no difference
Patient-Reported Penile Sensory Loss, Not Surgical Approach, Is Associated with Sexual Satisfaction After Inflatable Penile Prosthesis Implantation penile prosthesis erectile dysfunction surgical outcomes sexual dysfunction
- Eye Autoimmunity to ED: Pure Speculation2026-04-08
A hypothesis paper proposes that autoimmune retinopathy might damage circadian-regulating retinal cells and thereby impair testosterone and nitric oxide signaling — no data included
A Hypothetical Circadian–Endocrine Pathway Linking Melanopsin-Expressing ipRGC Dysfunction in Autoimmune Retinopathy to Sexual Dysfunction erectile dysfunction sexual dysfunction immunology biomarkers
- Six Providers, Five Sessions, No Patients Tested Yet2026-04-08
Sexual dysfunction affects 20–50% of childhood cancer survivors; six oncology providers spent 5 co-design sessions building a screening prototype — none of it tested on patients yet
Provider-Engaged Development of a Sexual Dysfunction Screening Approach for Adolescents and Young Adult Childhood Cancer Survivors: Iterative Co-Design Study screening sexual dysfunction survivorship health services
- Fasting Hormone Reverses SSRI Sexual Side Effects — In Rats2026-04-05
Asprosin injected directly into rat brains reversed paroxetine-induced erectile dysfunction, sperm loss, and testicular damage across all 5 endpoints measured
Asprosin Infusion Modulates Central Circuits to Rescue Selective Serotonin Reuptake Inhibitor-Induced Male Dysfunction antidepressants sexual dysfunction animal study semen quality
- Sexual Medicine Has a Pleasure Problem2026-04-02
An editorial argues clinical sexual medicine neglects justice, rights, and pleasure — proposing a shift from fixing dysfunction to enabling well-being
Sexual Health Framing Sexual Medicine: Toward a More Humanistic Framework sexual dysfunction evidence quality women's health health services
- Stroke, Parkinson's, MS All Disrupt Bladder2026-04-02
Review maps how neural damage from cortex to ganglia produces distinct bladder and sexual dysfunction across 10+ neurological conditions
Urogenital Dysfunction in Neurological Diseases Parkinson's disease multiple sclerosis sexual dysfunction erectile dysfunction
- Web Therapy Helps ED—If Men Stick With It2026-04-02
21 studies found online CBT improved erectile function; ED remission rates were 20–30%, but fewer than 60% of participants stayed engaged
Internet-Based CBT and Online Counseling for Male Sexual Dysfunction: Systematic Review erectile dysfunction sexual dysfunction evidence quality
- Your Antidepressant Has an 80% Sexual Side Effect Rate2026-04-01
Antidepressants cause sexual dysfunction in 25–80% of patients; antipsychotics in 16–60% — and most psychiatrists aren't asking
Psychiatric Disorders, Psychopharmacology and Sexual Dysfunction (ICSM 2024) antidepressants antipsychotics sexual dysfunction evidence quality
- Cancer Clinics Are Dropping the Ball on Sexual Health2026-04
Sexual dysfunction is common across cancer types but rarely addressed in oncology care, per this narrative review — no numbers provided
Oncosexology: A Narrative Review on Sexual Health and Quality of Life in Cancer Patients sexual dysfunction survivorship narrative review women's health
- Female Sexual Dysfunction: Still Going Unasked2026-03-24
A PA-focused clinical review covering FSD classification, risk factors, and treatments — no original data, no reported effect sizes
Female Sexual Dysfunction: Screening, Diagnosis, and Management sexual dysfunction women's health evidence quality screening
- After Prostate Surgery, Literacy Predicts Who Actually Follows Through2026-03-20
Men with low health literacy were 71% less likely to maintain ≥80% rehab adherence after prostatectomy, per a Chinese single-center study of 1,615.
Health Literacy Correlates, Barriers, and Adherence in Post-Prostatectomy Sexual Rehabilitation: Cross-Sectional Findings from China prostate cancer sexual dysfunction cross-sectional health services survivorship
- Years Playing, Not Injury Severity, Predicts Bladder Control2026-03-18
In 69 paralyzed rugby players, years of sport participation predicted bladder control better than injury classification did
Urinary Symptoms and Sexual Dysfunction in National Level Wheelchair Rugby Male Athletes With Spinal Cord Injury sexual dysfunction erectile dysfunction cross-sectional spinal cord injury
- Vaginal Surgical Access Rarely Damages Sex Life2026-03-18
Across 30 studies and 2,488 women, transvaginal specimen extraction showed low rates of postoperative dyspareunia and no clinically meaningful decline in sexual function scores.
Dyspareunia and Sexual Dysfunction After Transvaginal Specimen Extraction — A Systematic Review surgical outcomes sexual dysfunction women's health systematic review
- ACE Inhibitors Beat Beta-Blockers for Female Sexual Function2026-03-17
ACEIs/ARBs improved all sexual function domains in hypertensive women; beta-blockers helped less, especially in uncontrolled hypertension (n=125, 3 months)
Sexual Function Among Hypertensive Females Receiving Beta-Blockers or ACEI/ARB and Thiazides: A Prospective Randomized Controlled Study sexual dysfunction cardiovascular disease women's health vascular health
- PE, Anxiety, and SSRIs: One Broken System2026-03-17
A 2026 narrative review maps how serotonin and BDNF link premature ejaculation to comorbid anxiety and depression — and makes a pitch for TCM adjuncts
Role of 5-HT and BDNF in Premature Ejaculation With Anxiety or Depression sexual dysfunction antidepressants traditional chinese medicine biomarkers
- Mood, Not Birth Method, Drives Postpartum Sexual Dysfunction2026-03-14
Sexual function scores hit a nadir 6–8 weeks postpartum and depression predicted decline better than delivery mode or breastfeeding
Longitudinal Trajectories and Psychosocial Predictors of Postpartum Sexual Dysfunction from Early Pregnancy to 12 Months Postpartum sexual dysfunction women's health pregnancy biomarkers
- Does Your Doctor Ask About Your Sex Life?2026-03-11
A 2026 review maps primary care's role in four sexual health conditions: ED, premature ejaculation, sexual pain, and low desire.
Addressing Sexual Health in Primary Care erectile dysfunction premature ejaculation sexual dysfunction health services narrative review
- MS Ruins Sex Life—For Nearly Everyone. Sample: 372026-03-11
87.5% of men with relapsing-remitting MS screened positive for ED in a 37-person self-selected online survey
Hidden Challenges: A Cross-Sectional Study on Prevalence and Determinants of Sexual Dysfunction in Men and Women with Multiple Sclerosis sexual dysfunction erectile dysfunction cross-sectional multiple sclerosis
- Your Antipsychotic Determines Which Sexual Side Effect You Get2026-03-07
Aripiprazole flagged for compulsive sexual behavior (ROR: 296.23); risperidone and paliperidone linked to decreased libido and anorgasmia — signals vary sharply by drug
Female Sexual Dysfunction Induced by Second-Generation Antipsychotic Drugs — A Disproportionality Analysis Based on the FAERS Database sexual dysfunction women's health antipsychotics pharmacovigilance
- Shockwave ED Stats Look Good. Patients Disagree.2026-03-07
LI-ESWT improved IIEF scores across 19 RCTs, but most studies failed to reach the minimally clinically important difference
A Close Look at the Evidence on Low-Intensity Shockwave Therapy in Erectile Dysfunction — A Systematic Review and Meta-Analysis of Randomized Controlled Trials erectile dysfunction meta-analysis evidence quality sexual dysfunction
- 1 in 4 Infertile Women at Risk for Sexual Dysfunction2026-03-01
25% of women and 7% of men newly diagnosed with unexplained infertility screen positive for sexual dysfunction
Sexual Functioning and Its Determinants in Couples with Unexplained Infertility infertility sexual dysfunction
- Three in Four Transplant Women Never Asked About Sex2026-03
74% of female transplant recipients reported no provider had asked about sexual health in the past year
Study of Sexual Health in Peri and Postmenopausal Solid Organ Transplant Recipients sexual dysfunction women's health survivorship cross-sectional
- Nurse Counseling Barely Moves Prostate Cancer Sex Scores2026-02-27
14-study meta-analysis finds nurse-led psychoeducational programs improve sexual function (SMD=0.31) and satisfaction (SMD=0.27) — effects just clear zero
Cancer Nursing Interventions for Sexual Function and Satisfaction in Men with Prostate Cancer: A Systematic Review and Meta-analysis prostate cancer meta-analysis sexual dysfunction survivorship
- Sexual Dysfunction as a Heart Disease Early Warning2026-02-22
ED may flag cardiovascular disease years before symptoms — the evidence for women lags far behind
Erectile and Clitoral Dysfunction as Harbingers of Cardiovascular Disease: A Perspective erectile dysfunction cardiovascular disease sexual dysfunction
- SSRIs Triple Orgasm Dysfunction Risk2026-02-21
High-certainty meta-analysis of 13 RCTs, but all data is from 1990–2014
Sexual dysfunction associated with selective serotonin reuptake inhibitors in adults with depression: a systematic review and meta-analysis sexual dysfunction antidepressants
- Which SSRI Hits Male Sexual Function Hardest?2026-02-07
Escitalopram and citalopram showed the strongest ED signals (ROR ~8) across 6.6 million FAERS reports; fluvoxamine's signal didn't reach significance
Male Sexual Dysfunction Associated with Selective Serotonin Reuptake Inhibitors (SSRIs): A Pharmacovigilance Disproportionality Analysis of FAERS Data antidepressants erectile dysfunction pharmacovigilance sexual dysfunction
- Menopause Hurts Sex. Here's What Actually Helps.2026-02-04
A Stanford review surveys GSM treatments — hormonal, nonhormonal, and device-based — without reporting a single effect size
The New Toolbox for Reducing Painful Sex in Menopause sexual dysfunction women's health evidence quality menopause
- Nerve-Sparing Rectal Surgery Still Harms 1 in 132026-01-30
Nerve-preserving rectal resection cut post-op sexual dysfunction to 7.7%, but IIEF-5 scores still fell significantly at 6 months.
Laparoscopic Rectal Cancer Resection With Pelvic Autonomic Nerve Preservation in Males: A Prospective Single-Center Study sexual dysfunction surgical outcomes
- More Kidney Stones, Worse Erections — But Why?2026-01-23
202 kidney stone patients surveyed: men with recurrent stones showed worse erectile function, women reported low arousal regardless of stone burden
Evaluating the Sexual Quality of Life of Kidney Stone Formers: A Multicentric Cross-Sectional Study kidney stones erectile dysfunction sexual dysfunction cross-sectional women's health
- Men Think Average Is Small. Research Agrees They're Wrong.2026-01-20
Only 7 studies exist on this topic — all found men overestimate what's "normal" in size and sexual performance while underestimating their own normalcy
Are Men Aware of Normal Penile Length and Sexual Function? A Narrative Review narrative review sexual dysfunction erectile dysfunction evidence quality
- Nearly All HIV-Positive Women in Study Report Low Libido2026-01-16
53% of sexually active HIV-positive women met criteria for sexual dysfunction; 94% screened positive for hypoactive sexual desire.
Sexual Dysfunction and Hypoactive Sexual Desire in Women Living With HIV in Ceará, Brazil: A Cross-Sectional Study sexual dysfunction HIV women's health cross-sectional
- 60% of Women With Parkinson's Report Sexual Dysfunction2026-01-16
60.7% of women with Parkinson's had sexual dysfunction vs 17.9% of controls — but the two measurement scales disagreed
Sexual Dysfunction in Parkinson's Disease: What About Women? sexual dysfunction women's health cross-sectional Parkinson's disease
- 39% of Women in Primary Care Have Sexual Dysfunction2026-01-06
39% prevalence of female sexual dysfunction in primary care — but the evidence base is five years stale
Female Sexual Dysfunction in Primary Care: A Systematic Review and Meta-Analysis of Prevalence sexual dysfunction meta-analysis evidence quality
- Asthma Hurts Women's Sex Life, Not Marriage2025-12-31
80 asthmatic women scored worse on sexual function and sexual quality of life than matched controls, but marital adjustment scores were similar
Does Asthma Affect Women's Sexual Life and Marital Adjustment? case-control study cross-sectional sexual dysfunction women's health
- Only 12% of Men Satisfied With Surgical Appearance2025-12-26
Only 12% of men with repaired bladder exstrophy were satisfied with genital appearance; 43% of women met criteria for sexual dysfunction
Long-term Sexual Outcomes in Classic Bladder Exstrophy: Insights from Standardized Scores bladder exstrophy pediatric urology sexual dysfunction erectile dysfunction surgical outcomes patient satisfaction retrospective cohort quality of life
- Vascular Surgery's Sexual Side Effects: Nobody's Talking2025-12-20
88% of male AAA patients were never warned their procedure could affect sexual function—yet it did
Sexual Function Following Elective Endovascular Surgery for Abdominal Aortic Aneurysm surgical outcomes sexual dysfunction vascular health women's health
- Sexual Problems Drive Dissatisfaction — Not Vice Versa2025-12-18
Sexual problems at baseline predicted lower satisfaction 2 years later, but satisfaction did not predict future problems — a one-way street in 83 couples
The Interrelationships Between Sexual Problems and Sexual Satisfaction: A Two-Year Longitudinal Study with Dyads sexual dysfunction quality of life longitudinal study relationship health
- When Pelvic Floor Therapy Conflicts With Trauma2025-12-17
~15% of French women report lifetime sexual violence; this review flags intravaginal PT as a trauma conflict for pelvic pain patients
Pelvic Floor Physical Therapy for Sexual Abuse Survivors With Pelvic Pain pelvic floor women's health sexual dysfunction narrative review vaginismus
- Labiaplasty Scores Better Sex on Paper2025-12-13
Pooled data from 6 studies show a moderate FSFI improvement (SMD 0.52) after labiaplasty, but low certainty undermines the finding
Sexual Function After Female Genital Cosmetic Surgery: A Systematic Review and Meta-Analysis meta-analysis surgical outcomes sexual dysfunction women's health evidence quality
- Painful Sex Tops QoL Concerns in Endometriosis2025-12-03
Dyspareunia was the dominant sexual dysfunction in 1,586 French endometriosis patients; the QoL-sex link disappeared in obese and low-education subgroups
Sexual Functioning and Quality of Life Among Women With Endometriosis: A French Cross-Sectional Survey cross-sectional sexual dysfunction women's health
- Venlafaxine Nearly Doubles Sexual Dysfunction Risk in Depressed Men2025-11-08
Venlafaxine raised sexual dysfunction risk 27% vs citalopram overall — and 93% higher among hospitalized depression patients
Sexual Dysfunction in Male Patients After Initiating Treatment with Antidepressants antidepressants sexual dysfunction pharmacovigilance cohort study
- Vaginal Dryness Correlates With Higher Sexual Interest — Somehow2025-09-10
195 postmenopausal Turkish women: pain during sex lowered sexual interest; vaginal dryness paradoxically correlated with higher interest
The Association Between Day-to-Day Impact of Vaginal Aging and Female Sexual Function menopause sexual dysfunction women's health cross-sectional
- Counseling Beats Silence for Pregnant Women's Sexual Function2025-08-27
Three counseling approaches improved sexual function scores in pregnant women — but 21 of 24 studies came from Iran
Non-pharmacologic therapies for treating sexual dysfunction during pregnancy: A systematic review and meta-analysis sexual dysfunction pregnancy
- A Rare Penile Condition With Almost No Research2025-07-07
Only 8 studies exist on hard-flaccid syndrome — most are case reports, leaving diagnosis and treatment without any established guidelines.
Hard-Flaccid Syndrome: A Systematic Review of Aetiopathophysiology, Clinical Presentation and Management erectile dysfunction sexual dysfunction systematic review pelvic floor case report
- Breast Cancer's Sexual Side Effects: Still Mostly Ignored2025-07-04
92% of breast cancer patients wanted systematic sexual health information; only 47% ever got any, and just 20% were screened
Information and Screening for Sexual Disorders of Patients with Non-Metastatic Breast Cancer: Results of a Survey sexual dysfunction screening survivorship women's health health services cross-sectional
- Sexual Self-Esteem Tracks Closely With ED and PE2025-07-04
In 5,665 German men at age 50, negative body image, low sexual self-esteem, and perceived sexual pressure each independently predicted ED, PE, and low libido (all p<0.001)
Dimensions of Sexual Self-Concept and Sexual Dysfunctions in Middle-Aged Men: Results of the Bavarian Men's Health Study erectile dysfunction sexual dysfunction cross-sectional epidemiology
- Glans Removal Outcomes Look Good — If You Squint2025-04-15
14 studies, 327 procedures: 91% retained erectile function after glansectomy, but outcome reporting was too inconsistent to draw firm conclusions
Functional Outcomes of Glansectomy to Treat Localised Penile Cancer: A Systematic Review penile cancer surgical outcomes sexual dysfunction evidence quality
- Robotic Surgery Halves Ejaculation Problems After Rectal Cancer2024-10-22
Robotic rectal surgery cut ejaculatory dysfunction from 41% to 25% vs. laparoscopic at 12 months — no edge on erections
Prospective Multicenter Comprehensive Survey on Male Sexual Dysfunction following Laparoscopic, Robotic, and Transanal Approaches for Rectal Cancer (the LANDMARC Study) surgical outcomes erectile dysfunction sexual dysfunction robotics quality of life