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← all papers · epigenetics (8) Science journalism, not medical advice.

Your Father's Chemical Exposure May Shape Your Health2026-06-03
Review links six ubiquitous EDC classes to sperm damage and transgenerational harm — paternal occupational exposure tied to low birth weight and congenital heart disease in offspring
Endocrine Disruption and Male Fertility environmental exposure epigenetics male infertility semen quality oxidative stress infertility
Plastic Chemicals May Rewrite Fertility Across Generations2026-05-08
A narrative review argues BPA harms male fertility via gut dysbiosis and epigenetic marks — but admits the transgenerational evidence is provisional at best
Transgenerational Exposure to Plastics-Derived Endocrine-Disrupting Bisphenol A and Its Analogs on Male Infertility: Impact of Gut Dysbiosis and Epigenetic Regulation environmental exposure epigenetics male infertility narrative review spermatogenesis gut microbiome
Semen Inflammation Signals Sperm DNA Damage — With Caveats2026-05-06
High sperm DNA fragmentation correlated with elevated NLRP3, caspase-1, IL-1β, and IL-18 — but the protein data came from only 5 men per group
Inflammasome-Related Markers and Long Non-Coding RNAs in Seminal Plasma: Associations with Sperm DNA Fragmentation and Male Infertility male infertility DNA fragmentation inflammation biomarkers epigenetics oxidative stress
One Gene Deletion Kills All Sperm Maturation in Mice2026-03-20
Knocking out a single gene in mice triggers complete male infertility by blocking the histone-to-protamine swap that compacts sperm DNA
PRAMEL12 orchestrates spermiogenesis to ensure male fertility in mice animal study male infertility spermatogenesis genetics epigenetics
AI Will Fix Male Infertility (Trust Us)2026-03-16
A solo computer scientist argues LLMs could transform male infertility research — with zero data to show for it
Future directions in infertility research: the role of generative AI and large language models. male infertility infertility genetics epigenetics
Why Is One-Third of Male Infertility Unexplained?2026-03-14
Male infertility causes 20–30% of all infertility cases globally, yet 30–40% of cases have no identified cause
Epidemiology, Etiopathogenesis, Diagnosis, and Treatment of Male Infertility — Current Trends and Future Directions: A Narrative Review male infertility epigenetics environmental exposure biomarkers
Mom's Diet Shapes Her Son's Sperm, in Cattle2026-03
Genetics explains only ~15% of male infertility; a cattle review argues epigenetic marks fill the gap — and pass across generations
Bull Fertility and Epigenetics: Exploring Influences Beyond Genetics animal study male infertility genetics epigenetics biomarkers
The Test Your Fertility Clinic Isn't Running2025-12-03
A narrative review arguing that histone modifications in sperm—disrupted by toxicants and lifestyle—may explain a large share of "unexplained" infertility cases.
Epigenetic Dysregulation in Idiopathic Male Infertility: The Role of Aberrant Histone Post-Translational Modifications epigenetics male infertility environmental exposure oxidative stress spermatogenesis