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· epigenetics (6)
Science journalism, not medical advice.
Plastic Chemicals May Rewrite Fertility Across Generations
2026-05-08
A narrative review argues BPA harms male fertility via gut dysbiosis and epigenetic marks — but admits the transgenerational evidence is provisional at best
Transgenerational Exposure to Plastics-Derived Endocrine-Disrupting Bisphenol A and Its Analogs on Male Infertility: Impact of Gut Dysbiosis and Epigenetic Regulation
environmental exposure
epigenetics
male infertility
narrative review
spermatogenesis
gut microbiome
One Gene Deletion Kills All Sperm Maturation in Mice
2026-03-20
Knocking out a single gene in mice triggers complete male infertility by blocking the histone-to-protamine swap that compacts sperm DNA
PRAMEL12 orchestrates spermiogenesis to ensure male fertility in mice
animal study
male infertility
spermatogenesis
genetics
epigenetics
AI Will Fix Male Infertility (Trust Us)
2026-03-16
A solo computer scientist argues LLMs could transform male infertility research — with zero data to show for it
Future directions in infertility research: the role of generative AI and large language models.
male infertility
infertility
genetics
epigenetics
Why Is One-Third of Male Infertility Unexplained?
2026-03-14
Male infertility causes 20–30% of all infertility cases globally, yet 30–40% of cases have no identified cause
Epidemiology, Etiopathogenesis, Diagnosis, and Treatment of Male Infertility — Current Trends and Future Directions: A Narrative Review
male infertility
epigenetics
environmental exposure
biomarkers
Mom's Diet Shapes Her Son's Sperm, in Cattle
2026-03
Genetics explains only ~15% of male infertility; a cattle review argues epigenetic marks fill the gap — and pass across generations
Bull Fertility and Epigenetics: Exploring Influences Beyond Genetics
animal study
male infertility
genetics
epigenetics
biomarkers
The Test Your Fertility Clinic Isn't Running
2025-12-03
A narrative review arguing that histone modifications in sperm—disrupted by toxicants and lifestyle—may explain a large share of "unexplained" infertility cases.
Epigenetic Dysregulation in Idiopathic Male Infertility: The Role of Aberrant Histone Post-Translational Modifications
epigenetics
male infertility
environmental exposure
oxidative stress
spermatogenesis
male infertility
96
sexual dysfunction
64
erectile dysfunction
58
surgical outcomes
53
biomarkers
47
evidence quality
44
spermatogenesis
43
genetics
43
animal study
40
semen quality
37
narrative review
35
women's health
34
oxidative stress
33
kidney stones
32
meta-analysis
29
cross-sectional
28
hypogonadism
26
infertility
26
testicular cancer
25
systematic review
24
health services
22
pediatric urology
19
environmental exposure
17
testosterone
16
survivorship
16
immunology
14
inflammation
14
vascular health
14
penile prosthesis
13
cohort study
13
obesity
12
testicular disease
12
pathology
12
traditional chinese medicine
12
penile cancer
12
metabolic syndrome
11
genomics
11
pelvic floor
10
hypospadias
9
screening
9
prostate cancer
9
epidemiology
8
testosterone therapy
8
cardiovascular disease
8
case report
8
pregnancy
7
antidepressants
7
retrospective cohort
6
quality of life
6
pharmacovigilance
6
epigenetics
6
stem cells
5
urinary incontinence
5
cryptorchidism
5
diabetes
4
robotics
4
antisperm antibodies
4
mental health
3
scoping review
3
BPH
3
patient satisfaction
3
neurodegenerative diseases
3
menopause
3
iron metabolism
3
sperm capacitation
3
varicocele
3
case-control study
3
HPV
3
DNA fragmentation
3
gut microbiome
2
autophagy
2
artificial intelligence
2
Peyronie's disease
2
Parkinson's disease
2
multiple sclerosis
2
antipsychotics
2
contraception
2
air pollution
2
paraneoplastic syndrome
1
exercise
1
tuberculosis
1
nanomedicine
1
spinal cord injury
1
occupational exposure
1
premature ejaculation
1
COVID-19
1
anabolic steroids
1
HIV
1
kidney cancer
1
bladder exstrophy
1
longitudinal study
1
relationship health
1
vaginismus
1