← all papers · case report (14) Science journalism, not medical advice.
- The Testicular Tumor That Fools Every Blood Test2026-06-19
A 21-year-old's painless testicular mass turned out to be a tumor type so rare it accounts for under 1% of testicular neoplasms — and all standard tumor markers came back normal.
Primary Testicular Neuroendocrine Tumor: Diagnostic Challenges and WHO 2022 Classification Insights case report testicular cancer testicular disease pathology biomarkers
- Penile Implant Restores Function—For One Man2026-06-05
Single-patient case report argues for earlier prosthesis referral after radical prostatectomy, with no data beyond one outcome
Restoring Sexual Health and Relationship Quality Through Penile Prosthesis Implantation case report erectile dysfunction penile prosthesis prostate cancer survivorship patient satisfaction
- Bile Pigment Spotted Where Kidney Stones Form2026-06-04
Red-orange crystals in 1.1% of Randall's plaque stones were identified as calcium bilirubinate — a bile pigment — possibly linked to liver disease.
Calcium Bilirubinate at the Randall's Plaque-Kidney Stone Interface: First Description kidney stones pathology retrospective cohort case report
- Two Men Failed IVF Until Doctors Checked Their DNA2026-06
Two novel PLCZ1 frameshift mutations caused near-total IVF failure; adding assisted oocyte activation pushed fertilization rates to 73–80%
Clinical Features and PLCZ1 Gene Variants in Two Cases of Male Infertility: A Case Series and Literature Review genetics genomics male infertility case report
- The Testicular "Heart Attack" That Wasn't Torsion2026-02-27
A single case of segmental testicular infarction resolved with heparin — no surgery, no orchiectomy
Segmental Testicular Infarction: A Case Report testicular disease case report
- Ultrasound Pattern Could Spare Testicles From Surgery2026-02-06
17 men with testicular sarcoidosis had tiny, stable nodules that mimicked cancer on ultrasound
Multiparametric Ultrasound Findings of Testicular Sarcoidosis testicular disease case report pathology testicular cancer
- Gene Variant Floods Sperm With Chromosome Errors2026-01-25
A single inherited frameshift variant left 18.8% of one man's sperm missing sex chromosomes entirely — and drove repeated miscarriages
Homozygous C12orf40 Variant Contributes to Severe Oligoasthenoteratozoospermia and Sperm Sex Chromosome Aneuploidy genetics male infertility spermatogenesis case report pregnancy
- Rare Scrotal Cyst Mistaken for Tumor, Costs a Testicle2026-01-19
Meconium periorchitis — a sterile scrotal mass affecting 1 in 30,000 newborns — is routinely misdiagnosed as teratoma, potentially driving unnecessary orchiectomy
Meconium Periorchitis case report pediatric urology testicular disease pathology
- When the "Tumor" Was Just Misplaced Spleen2025-11-17
A 10-year-old's para-testicular "tumors" turned out to be ectopic splenic tissue — a rare anomaly that can prevent unnecessary surgery if recognized
An Unexpected Bond: Unraveling a Case of Spleno-Gonadal Fusion Anomaly Mistaken for Lymph Node and Testicular Tumor case report cryptorchidism pediatric urology testicular disease pathology
- Two Brothers, One Gene, Zero Sperm Motility2025-11-11
Two siblings share novel homozygous DNHD1 mutations causing severe flagellar defects and near-total sperm immotility
Novel Biallelic *DNHD1* Variants Associated with Male Infertility with Severe MMAF Phenotype genetics male infertility semen quality case report
- Mutant DNA Repair Gene Found in Two Infertile Men2025-09-15
Two men with severe OAT carried novel loss-of-function variants in MDC1, a DNA damage checkpoint protein — one ICSI attempt failed
Novel Variants in MDC1 are Associated With Severe Oligoasthenoteratozoospermia genetics male infertility semen quality case report
- A Rare Penile Condition With Almost No Research2025-07-07
Only 8 studies exist on hard-flaccid syndrome — most are case reports, leaving diagnosis and treatment without any established guidelines.
Hard-Flaccid Syndrome: A Systematic Review of Aetiopathophysiology, Clinical Presentation and Management erectile dysfunction sexual dysfunction systematic review pelvic floor case report
- A Boy's Rare Mutation, Recreated in Mice2025-06-03
One boy's gene mutation was knocked into mice, who developed undescended testes and poor sperm quality
Cryptorchidism: Novel genetic insights into CCDC149 mutations cryptorchidism genetics animal study case report
- Four Patients, Three Conflicts, One Recommendation2024-03-05
A 4-patient case series — with manufacturer financial ties declared by 3 of 5 authors — reports high satisfaction with a subcutaneous silicone penile implant post-prostatectomy.
Himplant® Subcutaneous Penile Implant Improves Penile Appearance and Erectile Dysfunction After Radical Prostatectomy: A Case Series penile prosthesis erectile dysfunction prostate cancer case report