← all papers · cryptorchidism (8) Science journalism, not medical advice.
- Female Fetal Ligaments Aren't Hormonally Passive2026-04-05
In first-trimester human fetuses, caudal genital ligaments in both sexes express receptors for androgens, estrogens, and INSL3 — the "passive female default" model doesn't hold in humans
Receptivity of the Human Male and Female Fetal Caudal Genital Ligament to Gonadal Hormones cryptorchidism pediatric urology environmental exposure pregnancy genomics
- In Cryptorchidism, the Support Cells Fail First2026-03-07
In a mouse cryptorchidism model, Sertoli and peritubular myoid cells show stress signals within 3 days — before germ cells begin dying
Somatic Cell Dysfunction Precedes Testicular Degeneration in a Surgical Model of Cryptorchidism cryptorchidism animal study pediatric urology spermatogenesis
- When a Boy's Anatomy Needs Genetic Answers First2026-03-04
In 43 children with proximal hypospadias, every patient had severe ventral chordee and most had an underlying disorder of sex development requiring workup before surgery
In Which Cases of Proximal Hypospadias Detailed Investigations Are Necessary pediatric urology cryptorchidism surgical outcomes hypospadias
- Vanished Testicles Rarely Harbor Cancer Risk2026-02-14
In 262 boys with absent testes, only 1.1% of remnants contained viable germ cells — and no malignancy was found in 15 years.
Testicular Regression Syndrome Revisited: Insights from a 15-Year Retrospective Study and Evolving Perspectives on Management pediatric urology cryptorchidism testicular disease surgical outcomes retrospective cohort
- Undescended Testes Wreck Fertility in Several Ways2026-01-09
A review maps the biological pathways from undescended testes to infertility — temperature, hormones, oxidative stress, and autoimmunity
Cryptorchidism and Infertility: What Do We Know So Far? male infertility cryptorchidism
- When the "Tumor" Was Just Misplaced Spleen2025-11-17
A 10-year-old's para-testicular "tumors" turned out to be ectopic splenic tissue — a rare anomaly that can prevent unnecessary surgery if recognized
An Unexpected Bond: Unraveling a Case of Spleno-Gonadal Fusion Anomaly Mistaken for Lymph Node and Testicular Tumor case report cryptorchidism pediatric urology testicular disease pathology
- Uterus in Males: A Hidden Infertility Cause2025-11-07
Only 1 in 5 men with PMDS have conceived naturally at time of diagnosis; most present with cryptorchidism or hernias
Persistent Müllerian Duct Syndrome - A Rare but Important Cause of Male Factor Infertility cryptorchidism male infertility narrative review pediatric urology
- A Boy's Rare Mutation, Recreated in Mice2025-06-03
One boy's gene mutation was knocked into mice, who developed undescended testes and poor sperm quality
Cryptorchidism: Novel genetic insights into CCDC149 mutations cryptorchidism genetics animal study case report